MODULE 1. Introduction & Objectives

• Welcome, presentation of the program, consent

MODULE 2. Pathophysiology of warts

• Virology: HPV, pathophysiology of warts (plantar, vulgaris, genital)

• Clinical differentiation of lesions (keratosis, molluscum, condylomas, etc.)​

• Immune cascade involved, contributing factors and transmission

MODULE 3. Principles of cryotherapy

• Mechanisms of action of liquid nitrogen (-196 °C), targeted cell destruction

• Protocols: duration of application, freeze-thaw cycles, indications according to the type of lesion

• Expected efficacy, physiology of healing

MODULE 4. Gesture safety and protocols

• Hygiene, disinfection, approved equipment, preparation of the operating field

• Precautions and monitoring during application (tolerance, tissue reaction)

• Side effects: pain, blister, scar, depigmentation

• Contraindications: suspected cancer, uncontrolled diabetes, circulatory disorders, immunosuppression, pregnancy (case to be discussed), keloid scars

• Management of complications, discontinuation of the procedure in case of intolerance

MODULE 5. Limits of the nursing field and legal responsibilities

• Need for a medical prescription or an authorized collective protocol

• Minimum age, types of injuries allowed, maximum number of sessions, mandatory documentation of the procedure

• Medical solicitation if treatment failure or clinical worsening

• Patient information rules, obtaining informed consent

MODULE 6. Technical demonstrations

• Patient preparation (cleaning, gentle debridement if necessary)

• Material Selection (Cryojet®, Cotton Swab, Gloves, Protection)

• Practical application on simulator (indications, duration, cycles, icing halo)

• Simulation on models: typical and special cases

MODULE 7. Supervised Practice

• Performing the gesture on a simulator

• Exercises on different types and locations of lesions

MODULE 8. Post-treatment follow-up, documentation and advice

• Follow-up planning every 2-3 weeks, maximum 5 sessions per lesion

• Post-care education, contamination prevention, patient recommendations (local care, non-scratching, monitoring healing)

• Rigorous documentation: gesture, material, observed effect, tolerance, follow-up planning

MODULE 9. Evaluation & feedback

• Theoretical quiz (safety, legislation, pathophysiology)

• Practical evaluation on a simulator

• Presentation of certificates

Appendices or Resources

• Examples of collective protocols and regulatory frameworks

• Patient Information Sheets

• Management algorithms: when to refer, when to continue